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Authors:Dr.Rachna Thakur,Dr.Sandya S Patil,Dr.Madhu K.

In the modern time the prevalence of dental caries cannot be denied. The conventional approach to the elimination of carious lesion was developed a century ago; this method was necessary at that time because there was no valid alternative. The conventional method for caries removal is usually carried out with high speed hand piece to access the lesion and a low speed hand piece to remove caries. Although, this method is quick and efficient in caries removal, it may result in unnecessary removal of sound tooth structure. In addition, caries removal with the conventional method is usually associated with pain, annoying sound and possibility of producing thermal and mechanical injuries to dental pulp. Furthermore, in children and patients with anxiety the conventional technique is often associated with discomfort.1Research over the last thirty years has made it possible to modify this approach to adopt the concept minimal invasive dentistry. There are many different treatment approaches for carious lesions depending upon causal factors, lesion stage and activity.  Minimal invasive dentistry can be defined as maximal preservation of healthy dental structures.2
Of all the possible options available for the removal of the carious lesion, the most acceptable one is Chemomechanical caries Removal (CMCR) system. CMCR technique introduced almost three decades ago was claimed to be a non-invasive alternative for the removal of carious dentin. The chemomechanical approach was initially introduced in 1972; with the technique involved applying a solution on to the decayed dentinal tissue to soften it and finally scrapping it off with the blunt hand instrument. The partially degraded collagen in carious dentin was softened by the gel due to the breakage of the peptide bond.3,4
After an extensive research at VittalMallya Scientific Research Foundation, a Ministry of Science and Technology, Govt of India approved Research Centre has developed a new formula Carie CareTM (Figure – 1), to universalize the use of chemomechanical method for caries removal and to promote its use in public health.Eco works India PvtLtd; Bangalore has launched the product with an aim to make it available to the large population at very reasonable price using efficient supply chain.
Carie careTM gel is basically comprised of papaya extract with essential therapeutic oils which together are responsible for the proteolytic action, antimicrobial, antiseptic and anti-inflammatory properties. The papaya extract has proteolytic action that would soften the pre degraded collagen of the lesion without pain or undesirable effects to adjacent healthy tissues with the antiseptic and anti-inflammatory properties of the essential therapeutic oils5,6.
The mechanism on which Carie careTM works is it cause degradation of the partially degradedcollagen (degrades intact non mineralized Type 1 collagen fibrils), present on the peripheral caries infected zone, which lacks the capacity to mineralized by cleavage of the polypeptide chains in the triple helix and/or hydrolysing the cross linkages. The polypeptide hydrolysis is brought about by endopeptidases extracted and purified to homogeneity from papaya extract.7,8
Ideal indications for the usage of Carie careTM are any carious lesion extending into the dentine. The cases may vary from the pin point or bottle neck caries into the dentine to the grossly carious lesion in the dentine. It is an established approach for the anxious patients and young paediatric patients. 

Fig-1.Carie CareTM,Eco works Pvt Ltd,Banglore,www.ecodentalworks.com

Case Report with the management: A 13 years old patient with the deep dentinal caries in relation to 36 without any clinical symptom of pain and sensitivity was selected (Figure -2A). The radiographic evaluation was done to confirm the extent of caries into the dentine with no pulpal involvement (Figure – 2B). The tooth was isolated using the proper isolation method (Figure -2C).

Fig-2:Steps Involved in caries excavation using Carie Care A-Open carious lesionirt 36,B- Radiographic evaluation of 36,C-Isolation of The tooth,D-Application of carie Care,E-followed of excavation,F- After preparation using carie care.

The caries excavation was done according to manufacturer’s instructions. The carious lesion was covered with the gel and left undisturbed for 30- 60 seconds (Figure -2D). The gel was removed by gently scrapping with the spoon excavator without applying pressure (Figure – 2E). Removal of the caries was continued until the hard and affected dentine appeared on the tooth. Then gel was removed and the cavity was wiped with the moistened cotton pellet and rinsed (Figure –2F).Once the cavity was confirmed free of caries, it was restored with the ideal adhesive restorative material after attaining proper isolation.

Discussion: Dentists are highly trained at using dental burs in slow speed or air turbine handpieces7. Moreover, the rotary instruments used often causes pain and are unpleasant to many patients and needs anaesthesia. Thus the advantages of using Carie care are: a) avoids painful removal of dentine b) fast action c) eliminates need of local anaesthesia d) provides more surface area which would be well suited to restoration with modern adhesive material e) no adverse effect on pulp and healthy tissues f) higher patient acceptance  with palatable taste g) conservation of the sound tooth structure and reduce chances of pulp exposure h) well suited to the treatment of anxious and medically compromised patients as well as to paediatrics and domiciliary dentistry i) scientific and clinical validation for its efficacy and safety by various in house and external accredited agencies including multiple dental colleges.10-13j) no adverse effect, side effects. The limitations cited for the use of CMCR agent are rotary instruments are still needed for removal of unsupported enamel. This includes the access to interproximal carious lesion. This is attributed to the site specific action of the gel as it acts only on the infected dentin, thus reducing the chances of iatrogenic removal of the healthy tissue.10The other problem ported by the operator in using CMCR technology is the time consumed for caries excavation. However with time and development of expertise the reverse took place with CMCR being less time consuming than conventional method as reported previously. This is attributed to lack of any specialized equipment and ease of procedure using CMCR products14
In a recent Indian clinical trial, comparative evaluation was done between Carie care and conventional rotary turbine as caries removal measures on pediatric patients. The results of the following study showed that the two techniques were comparable in caries removal efficiency and re­moval of caries by Carie care was pain less, non-invasive, safe and more patient friendly 15.

Conclusion:This introduction of predictable caries removal technologies has led to a giant step in interest in minimal invasive dentistry. This will help in selective approach between prevention and surgical procedures, which just dentistry needs today. Development of a clinically effective CMCR, like Carie care, which is harmless to healthy tissue and bio-compatible, has given a conservative and optimal clinical approach to the management of the extensive caries. It also provides a unique opportunity in propagating pain-less bondage between patient and dentist  and help the oral health care personnel in exploring the ever increasing avenues and opportunities to follow the concept of Painless dentistry.



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